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In mammals, the current data propose that venous derived LECs, hematopoietic cell derived circulating endothelial progenitors CEPs, and transdifferentiating leukocytes and macrophages are putative sources of LECs during embryonic and adult lymphangiogenesis in health and disease Wigle and Oliver 1999; Wigle et al stromectol 12 mg Drug therapy effects usually emerge a few months following initiation and disappear after drug withdrawal 23
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